CDH19

Across TCGA cell cohorts, CDH19 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,004 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDH19-associated GO terms across cancer lineages are Regulation of protein K63-linked ubiquitination, Cytokinetic process, and Negative regulation of microglial cell activation. Each is linked with CDH19 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDH19-to-partner and partner-to-CDH19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein K63-linked ubiquitination grouped by CDH19-low versus CDH19-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH19→partner) and Y-score (partner→CDH19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein K63-linked ubiquitination →	+0.081	+0.626	.001	.004	3	4
BREAST	Cytokinetic process →	+0.056	+0.609	<.001	.005	3	4
KIDNEY	Negative regulation of microglial cell activation →	-0.208	-0.028	.005	.008	3	4
BLOOD_Leukemia	Positive regulation of SREBP signaling pathway →	+0.030	+0.018	.008	.006	3	4
KIDNEY	Assembly of actomyosin apparatus involved in cytokinesis →	+0.137	+0.018	.005	.007	2	4
KIDNEY	Actomyosin contractile ring assembly →	+0.137	+0.018	.005	.007	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,004 associations by consensus.

Regulation of protein K63-linked ubiquitination by CDH19 expression — BREAST

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