CDH17

Across TCGA pan-cancer cohorts, CDH17 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CDH17’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CDH17 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CDH17 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD, PDAC, and CCRCC are the cancer types where CDH17 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDH17 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−0.573	<.001	7	view →
PDAC	Female	III,IV	+1.958	.009	5	view →
CCRCC	All	All	+0.498	.004	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CDH17–COAD

Open the COAD breakdown →