CDH17

Across TCGA patient cohorts, CDH17 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,147 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDH17-associated GO terms across cancer lineages are COPII-coated vesicle cargo loading, Autophagosome organization, and Regulation of cellular response to transforming growth factor beta stimulus. Each is linked with CDH17 in more than 18 cancer types. Because this analysis shows association rather than direction, both CDH17-to-partner and partner-to-CDH17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle cargo loading grouped by CDH17-low versus CDH17-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH17→partner) and Y-score (partner→CDH17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	COPII-coated vesicle cargo loading →	+0.068	+2.516	<.001	<.001	3	19
THYM	Autophagosome organization →	+0.048	+0.326	<.001	<.001	3	18
THYM	Regulation of cellular response to transforming growth factor beta stimulus →	+0.051	+0.270	<.001	<.001	3	18
UVM	Nuclear membrane organization →	+0.051	+0.146	<.001	.003	3	18
UVM	Organelle disassembly →	+0.048	+0.209	<.001	<.001	3	18
THYM	Regulation of vacuole organization →	+0.060	+0.212	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,147 associations by consensus.

COPII-coated vesicle cargo loading by CDH17 expression — ESCA

Explore this box plot interactively →