CDH17

Across TCGA patient cohorts, CDH17 protein abundance is significantly associated with the RNA expression of many other genes, with 8,067 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CDH17-associated genes across cancer lineages are SMURF2, PTPN14, and NXN. Each is linked with CDH17 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDH17-to-partner and partner-to-CDH17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH17 versus SMURF2 in LUAD, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH17→partner) and Y-score (partner→CDH17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SMURF2 →	-0.576	-1.239	.006	.005	3	3
PDAC	PTPN14 →	-0.665	-1.342	<.001	<.001	3	3
COAD	NXN →	-1.110	-0.657	<.001	<.001	3	3
LUAD	TANC2 →	-0.676	-1.385	.004	.008	3	3
PDAC	RNF186 →	+1.419	+1.449	<.001	<.001	3	3
LUAD	FAM225A →	-0.216	-1.035	.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,067 associations by consensus.

CDH17 vs SMURF2 — LUAD

Explore this scatter interactively →