CDCP2

Across TCGA patient cohorts, CDCP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,034 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CDCP2-associated GO terms across cancer lineages are Regulation of canonical Wnt signaling pathway, Positive regulation of Wnt signaling pathway, and Import into nucleus. Each is linked with CDCP2 in more than 23 cancer types. Because this analysis shows association rather than direction, both CDCP2-to-partner and partner-to-CDCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of canonical Wnt signaling pathway grouped by CDCP2-low versus CDCP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCP2→partner) and Y-score (partner→CDCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of canonical Wnt signaling pathway →	+0.057	+0.050	<.001	<.001	3	24
STAD	Positive regulation of Wnt signaling pathway →	+0.061	+0.052	<.001	<.001	3	24
SCLC	Import into nucleus →	+0.072	+0.163	.001	.002	2	24
SCLC	Positive regulation of canonical Wnt signaling pathway →	+0.076	+0.188	<.001	<.001	2	24
SCLC	Positive regulation of stem cell population maintenance →	+0.096	+0.217	<.001	<.001	3	23
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.065	+0.053	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,034 associations by consensus.

Regulation of canonical Wnt signaling pathway by CDCP2 expression — STAD

Explore this box plot interactively →