CDCP2

Across TCGA pan-cancer cohorts, CDCP2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CDCP2’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where CDCP2 RNA is repressed in tumor relative to normal tissue. In most cancer types CDCP2 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

UCEC, THCA, and KIRP are the cancer types where CDCP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDCP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.103	.005	8	view →
THCA	Female	II,III,IV	−0.046	<.001	8	view →
KIRP	Male	All	−0.080	<.001	7	view →
BRCA	Female	All	−0.072	<.001	6	view →
LUSC	Male	II,III,IV	−0.046	.004	3	view →
CHOL	All	All	+0.108	.039	1	view →
KICH	Female	All	−0.074	.032	1	view →
LUAD	Female	All	−0.028	.037	1	view →
HNSC	Female	III,IV	+0.028	.035	1	view →
STAD	Male	All	−0.022	.023	1	view →
LIHC	Female	III,IV	−0.016	.013	1	view →
LIHC	All	All	+0.012	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

CDCP2–UCEC

Open the UCEC breakdown →