CDCP2

Across TCGA patient cohorts, CDCP2 mutation is significantly associated with the RNA expression of many other genes, with 2,238 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCP2-associated genes across cancer lineages are UHRF1, GPATCH11, and CWC27. Each is linked with CDCP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDCP2-to-partner and partner-to-CDCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UHRF1 grouped by CDCP2-low versus CDCP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCP2→partner) and Y-score (partner→CDCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UHRF1 →	+0.783	+2.098	.001	.003	3	3
SKCM	GPATCH11 →	+0.619	+2.379	.004	.003	3	3
UCEC	CWC27 →	+0.489	+2.724	.003	.003	3	3
UCEC	SKA1 →	+0.547	+3.343	.009	.005	3	3
UCEC	LARP7 →	+0.582	+3.732	.001	<.001	3	3
UCEC	PDIK1L →	+0.427	+2.512	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,238 associations by consensus.

UHRF1 by CDCP2 expression — UCEC

Explore this box plot interactively →