CDCP2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CDCP2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CDCP2-associated genes across cancer lineages are USP17L22, C6orf118, and ADAD1. Each is linked with CDCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCP2-to-partner and partner-to-CDCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L22 grouped by CDCP2-low versus CDCP2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCP2→partner) and Y-score (partner→CDCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaUSP17L22 →+0.019+4.643<.001.00532
LARGE_INTESTINEC6orf118 →+0.175+3.793<.001.00731
LUNG_NSCLC_LUADADAD1 →+0.048+4.371<.001.00531
BLOOD_LeukemiaSERPINA7 →+0.055+4.922<.001.00931
BLOOD_LymphomaOR10W1 →+0.024+4.643<.001.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

USP17L22 by CDCP2 expression — BLOOD_Lymphoma

Box plot of USP17L22 in CDCP2-low vs CDCP2-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration