CDCA8

Across TCGA patient cohorts, CDCA8 mutation is significantly associated with the RNA expression of many other genes, with 1,134 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA8-associated genes across cancer lineages are PGBD4P6, RN7SKP107, and MIR549A. Each is linked with CDCA8 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDCA8-to-partner and partner-to-CDCA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGBD4P6 grouped by CDCA8-low versus CDCA8-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA8→partner) and Y-score (partner→CDCA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PGBD4P6 →	+0.198	+6.593	<.001	<.001	3	3
LUSC	RN7SKP107 →	+0.357	+5.578	<.001	.002	3	2
LUSC	MIR549A →	+0.700	+4.625	<.001	.008	3	2
LUSC	RNA5SP86 →	+0.877	+6.593	<.001	<.001	3	2
LUSC	MIR1202 →	+0.613	+6.327	<.001	<.001	3	2
LUSC	RN7SKP263 →	+0.624	+5.309	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,134 associations by consensus.

PGBD4P6 by CDCA8 expression — LUSC

Explore this box plot interactively →