CDCA5

Across TCGA patient cohorts, CDCA5 mutation is significantly associated with the RNA expression of many other genes, with 142 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible CDCA5-associated genes across cancer lineages are DEFB123, RNA5SP205, and MIR4666B. Each is linked with CDCA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA5-to-partner and partner-to-CDCA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB123 grouped by CDCA5-low versus CDCA5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA5→partner) and Y-score (partner→CDCA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	DEFB123 →	+0.194	+3.691	<.001	.004	3	2
UCEC	RNA5SP205 →	+0.599	+3.852	<.001	.002	3	2
SKCM	MIR4666B →	+1.066	+3.933	.009	.007	3	2
UCEC	SNORD11B →	+0.784	+3.061	<.001	.002	3	1
SKCM	LINC01937 →	+0.084	+4.351	.001	.002	3	1
SKCM	SMIM2-IT1 →	+0.170	+3.992	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 142 associations by consensus.

DEFB123 by CDCA5 expression — BLCA

Explore this box plot interactively →