CDCA5

Across TCGA pan-cancer cohorts, CDCA5 RNA is linked to patient survival in 31 of 34 cancer types, making it the most broadly survival-associated CDCA5 data layer compared with 4 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CDCA5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CDCA5 expression acts as an unfavorable survival marker, although some lineages such as UCS and STAD show a favorable association.

ACC, MESO, and KIRP are the cancer types where CDCA5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.361	0.797	<.001	170	view →
MESO	OS	Median	All	0.352	0.733	<.001	141	view →
KIRP	DFS	Median	All	0.765	0.933	<.001	131	view →
KICH	DFS	Quartile	II,III,IV	0.447	1.000	<.001	103	view →
LIHC	DFS	Median	All	0.449	0.630	<.001	84	view →
KIRC	DFS	Tertile	All	0.516	0.666	<.001	77	view →
PAAD	DFS	Tertile	All	0.181	0.465	<.001	66	view →
LUAD	OS	Median	All	0.757	0.866	<.001	56	view →
LGG	OS	Median	All	0.748	0.875	<.001	49	view →
UCS	OS	Median	All	0.543	0.194	.001	46	view →
UCEC	OS	Quartile	All	0.830	0.947	<.001	32	view →
SARC	DFS	Tertile	All	0.516	0.716	<.001	30	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 31 lineages.

CDCA5–ACC (DFS)

Open the ACC breakdown →