CDCA5

Across TCGA patient cohorts, CDCA5 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA5-associated genes across cancer lineages are Endothelial cells, Th1 cells, and Th2 cells. Each is linked with CDCA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA5-to-partner and partner-to-CDCA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by CDCA5-low versus CDCA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA5→partner) and Y-score (partner→CDCA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.048	-2.957	.029	.037	2	1
UCEC	Th1 cells →	-0.137	-3.000	.011	.037	2	1
UCEC	Th2 cells →	+0.347	+3.000	<.001	.037	2	1
UCEC	lymphatic Endothelial cells →	-0.029	-2.946	.032	.037	1	1
UCEC	mv Endothelial cells →	-0.035	-2.989	.011	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Endothelial cells by CDCA5 expression — UCEC

Explore this box plot interactively →