CDCA4P4

Across TCGA pan-cancer cohorts, CDCA4P4 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CDCA4P4’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CDCA4P4 RNA is repressed in tumor relative to normal tissue. In most cancer types CDCA4P4 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, THCA, and BRCA are the cancer types where CDCA4P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDCA4P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.462	<.001	10	view →
THCA	All	All	−0.290	<.001	8	view →
BRCA	Female	All	−0.194	<.001	8	view →
LUSC	Female	II,III,IV	−0.635	<.001	7	view →
KICH	Female	All	−0.544	<.001	7	view →
KIRP	Male	II,III,IV	−0.319	<.001	6	view →
UCEC	All	All	−0.378	<.001	2	view →
READ	All	III,IV	−0.339	.048	2	view →
CHOL	All	All	+0.403	.027	1	view →
ESCA	All	All	+0.281	.009	1	view →
STAD	Male	II,III,IV	+0.197	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CDCA4P4–LUAD

Open the LUAD breakdown →