CDC5L

Across TCGA cell cohorts, CDC5L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,706 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDC5L-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Negative regulation of G2/M transition of mitotic cell cycle, and Negative regulation of cell cycle G2/M phase transition. Each is linked with CDC5L in more than 18 cancer types. Because this analysis shows association rather than direction, both CDC5L-to-partner and partner-to-CDC5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by CDC5L-low versus CDC5L-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC5L→partner) and Y-score (partner→CDC5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of RNA export from nucleus →	+0.170	+0.740	<.001	<.001	3	19
OVARY	Negative regulation of G2/M transition of mitotic cell cycle →	+0.061	+0.725	<.001	<.001	3	18
BONE	Negative regulation of cell cycle G2/M phase transition →	+0.090	+0.705	.003	<.001	2	19
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle phase transition →	+0.099	+0.735	<.001	<.001	3	17
STOMACH	Protein localization to condensed chromosome →	+0.157	+0.655	<.001	<.001	3	17
KIDNEY	Regulation of mitotic sister chromatid segregation →	+0.115	+0.606	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,706 associations by consensus.

Negative regulation of RNA export from nucleus by CDC5L expression — PANCREAS

Explore this box plot interactively →