CDC45

Across TCGA patient cohorts, CDC45 RNA expression is significantly associated with the RNA expression of many other genes, with 18,877 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CDC45-associated genes across cancer lineages are FANCD2, BRCA1, and POLE2. Each is linked with CDC45 in more than 33 cancer types. Because this analysis shows association rather than direction, both CDC45-to-partner and partner-to-CDC45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC45 versus FANCD2 in LIHC, with a Pearson correlation of 0.88.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC45→partner) and Y-score (partner→CDC45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	FANCD2 →	+1.323	+1.779	<.001	<.001	3	34
DLBC	BRCA1 →	+1.659	+1.221	<.001	<.001	3	34
ACC	POLE2 →	+1.217	+1.849	<.001	<.001	3	33
ACC	ASF1B →	+2.508	+2.244	<.001	<.001	3	33
KICH	ECT2 →	+1.847	+1.042	<.001	.001	3	33
THYM	CENPA →	+2.476	+2.119	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,877 associations by consensus.

CDC45 vs FANCD2 — LIHC

Explore this scatter interactively →