CDC45

Across TCGA cell cohorts, CDC45 RNA expression is significantly associated with the RNA expression of many other genes, with 10,928 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDC45-associated genes across cancer lineages are MCM5, RANBP1, and RAD51. Each is linked with CDC45 in more than 18 cancer types. Because this analysis shows association rather than direction, both CDC45-to-partner and partner-to-CDC45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC45 versus MCM5 in BONE, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC45→partner) and Y-score (partner→CDC45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	MCM5 →	+1.895	+1.896	<.001	.001	3	19
OESOPHAGUS	RANBP1 →	+1.329	+1.615	<.001	<.001	3	19
BONE	RAD51 →	+1.372	+1.738	<.001	.002	3	19
BLOOD_Myeloma	CDC6 →	+1.843	+2.056	.001	<.001	3	19
BLOOD_Myeloma	CENPM →	+1.605	+1.636	<.001	.001	3	18
BLOOD_Myeloma	TIMELESS →	+1.616	+2.182	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,928 associations by consensus.

CDC45 vs MCM5 — BONE

Explore this scatter interactively →