CDC42EP4

Across TCGA patient cohorts, CDC42EP4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDC42EP4-associated genes across cancer lineages are CPSF4L, AKAP1, and SUSD4. Each is linked with CDC42EP4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC42EP4-to-partner and partner-to-CDC42EP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC42EP4 versus CPSF4L in LSCC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42EP4→partner) and Y-score (partner→CDC42EP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CPSF4L →	+0.546	+0.344	<.001	<.001	3	6
BRCA	AKAP1 →	+0.676	+0.406	<.001	.001	3	5
OV	SUSD4 →	+1.098	+0.380	.007	.005	3	5
LSCC	CERS3-AS1 →	+0.834	+0.272	.003	.005	3	5
UCEC	TGFBR3 →	+0.713	+0.324	<.001	<.001	3	5
UCEC	DOC2B →	+1.349	+0.484	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,742 associations by consensus.

CDC42EP4 vs CPSF4L — LSCC

Explore this scatter interactively →