CDC42BPG

Across TCGA patient cohorts, CDC42BPG mutation is significantly associated with the RNA expression of many other genes, with 3,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42BPG-associated genes across cancer lineages are SAMD11, MIR103A1, and TAF9. Each is linked with CDC42BPG in more than 3 cancer types. Because this analysis shows association rather than direction, both CDC42BPG-to-partner and partner-to-CDC42BPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAMD11 grouped by CDC42BPG-low versus CDC42BPG-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPG→partner) and Y-score (partner→CDC42BPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SAMD11 →	-0.628	-2.780	.002	.003	3	4
COAD	MIR103A1 →	+0.345	+3.605	<.001	.002	3	4
UCEC	TAF9 →	+0.580	+3.108	<.001	<.001	3	3
UCEC	VPS29 →	+0.338	+2.101	.001	<.001	3	3
UCEC	ZWINT →	+0.664	+2.403	<.001	<.001	3	3
UCEC	SLC25A39 →	+0.321	+1.566	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,165 associations by consensus.

SAMD11 by CDC42BPG expression — COAD

Explore this box plot interactively →