CDC42BPG

Across TCGA patient cohorts, CDC42BPG mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC42BPG-associated genes across cancer lineages are eEF2, Caspase-7-cleavedD198, and GAPDH. Each is linked with CDC42BPG in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC42BPG-to-partner and partner-to-CDC42BPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CDC42BPG-low versus CDC42BPG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPG→partner) and Y-score (partner→CDC42BPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.286	+1.362	.023	.037	3	3
UCEC	Caspase-7-cleavedD198 →	+0.508	+2.459	.015	.018	3	3
STAD	GAPDH →	+0.579	+3.000	<.001	.034	3	2
UCEC	4E-BP1 →	+0.336	+2.351	<.001	.003	3	2
UCEC	14-3-3_beta →	-0.089	-2.673	.012	.005	3	2
UCEC	eIF4E →	+0.148	+1.750	.046	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

eEF2 by CDC42BPG expression — UCEC

Explore this box plot interactively →