CDC42BPG

Across TCGA cell cohorts, CDC42BPG RNA expression is significantly associated with the go_rna of many other GO terms, with 6,138 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDC42BPG-associated GO terms across cancer lineages are Negative regulation of Arp2/3 complex-mediated actin nucleation, Cytotoxic T cell degranulation, and Response to indole-3-methanol. Each is linked with CDC42BPG in more than 16 cancer types. Because this analysis shows association rather than direction, both CDC42BPG-to-partner and partner-to-CDC42BPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Arp2/3 complex-mediated actin nucleation grouped by CDC42BPG-low versus CDC42BPG-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPG→partner) and Y-score (partner→CDC42BPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.217	+1.846	.004	.008	2	17
LIVER	Cytotoxic T cell degranulation →	+0.328	+1.665	<.001	<.001	3	14
OESOPHAGUS	Response to indole-3-methanol →	+0.208	+1.784	<.001	.008	3	13
URINARY_TRACT	Negative regulation of RNA catabolic process →	+0.071	+2.593	.001	<.001	3	13
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	-0.260	-2.970	<.001	<.001	3	13
LIVER	mRNA stabilization →	+0.092	+1.301	.003	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,138 associations by consensus.

Negative regulation of Arp2/3 complex-mediated actin nucleation by CDC42BPG expression — OESOPHAGUS

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