CDC42BPG

Across TCGA cell cohorts, CDC42BPG mutation is significantly associated with the RNA expression of many other genes, with 400 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDC42BPG-associated genes across cancer lineages are OR56B1, TECTB, and PSMD9. Each is linked with CDC42BPG in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC42BPG-to-partner and partner-to-CDC42BPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56B1 grouped by CDC42BPG-low versus CDC42BPG-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42BPG→partner) and Y-score (partner→CDC42BPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR56B1 →	+0.016	+5.977	<.001	.001	3	2
PANCREAS	TECTB →	+0.656	+3.426	<.001	.003	3	2
LARGE_INTESTINE	PSMD9 →	+0.442	+3.169	<.001	.009	3	2
LARGE_INTESTINE	NDUFB10 →	+0.468	+3.237	.002	.003	3	2
LARGE_INTESTINE	MAPT →	+0.987	+3.169	.001	.009	3	2
BLOOD_Leukemia	KCNJ11 →	+1.532	+3.351	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 400 associations by consensus.

OR56B1 by CDC42BPG expression — SOFT_TISSUE

Explore this box plot interactively →