CDC42

Across TCGA patient cohorts, CDC42 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,557 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDC42-associated proteins across cancer lineages are FXN, LUZP1, and PEX14. Each is linked with CDC42 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDC42-to-partner and partner-to-CDC42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC42 versus FXN in PDAC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42→partner) and Y-score (partner→CDC42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FXN →	-0.331	-0.341	<.001	<.001	3	6
OV	LUZP1 →	+0.383	+0.495	<.001	<.001	3	6
PDAC	PEX14 →	+0.326	+0.323	.001	.001	3	5
LSCC	SLC9A1 →	+0.470	+0.400	<.001	<.001	3	5
OV	LDLRAP1 →	+0.400	+0.398	.005	.007	3	5
OV	RPS6KA1 →	+0.312	+0.467	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,557 associations by consensus.

CDC42 vs FXN — PDAC

Explore this scatter interactively →