CDC34

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDC34 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,650 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDC34-associated proteins across cancer lineages are CRELD2, SGTA, and THOP1. Each is linked with CDC34 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDC34-to-partner and partner-to-CDC34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC34 versus CRELD2 in LSCC, with a Pearson correlation of -0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC34→partner) and Y-score (partner→CDC34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCRELD2 →-0.549-0.500<.001<.00135
GBMSGTA →+0.390+0.501<.001<.00135
UCECTHOP1 →+0.217+0.765<.001<.00135
GBMEVI2B_S268 →-0.771-0.497<.001<.00135
COADREPIN1 →+0.329+0.373.003.00334
COADSFSWAP →+0.389+0.390.004.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,650 associations by consensus.

CDC34 vs CRELD2 — LSCC

Per-sample scatter of CDC34 vs CRELD2 in LSCC (Pearson r = -0.58).

Explore this scatter interactively →

Exploration