CDC34

Across TCGA pan-cancer cohorts, CDC34 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of CDC34’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CDC34 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CDC34 is over-expressed in tumor.

KIRC, COAD, and KIRP are the cancer types where CDC34 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDC34 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.749	<.001	12	view →
COAD	Male	IV	+1.338	<.001	11	view →
KIRP	Male	III,IV	+0.909	<.001	11	view →
LUAD	All	III,IV	+0.767	<.001	11	view →
LIHC	Female	All	+0.809	<.001	8	view →
THCA	Female	II,III,IV	+0.533	<.001	8	view →
STAD	Male	II,III,IV	+0.822	<.001	7	view →
HNSC	All	II,III,IV	+0.322	.001	7	view →
LUSC	Male	II,III,IV	+0.782	<.001	6	view →
BLCA	All	All	+0.616	.001	6	view →
UCEC	All	III,IV	+0.566	<.001	6	view →
READ	All	All	+0.713	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

CDC34–KIRC

Open the KIRC breakdown →