CDC34

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDC34 protein abundance is significantly associated with the RNA expression of many other genes, with 12,059 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDC34-associated genes across cancer lineages are CCL14, PAICS, and NOVA1. Each is linked with CDC34 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDC34-to-partner and partner-to-CDC34 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC34 versus CCL14 in CCRCC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC34→partner) and Y-score (partner→CDC34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCCCL14 →-0.631-0.167<.001.00135
LUADPAICS →+0.586+0.275<.001<.00134
BRCANOVA1 →-1.171-0.249.002<.00134
COADGAPDH →+0.662+0.679<.001<.00134
LUADDLGAP5 →+1.196+0.302<.001<.00134
LUADKNSTRN →+0.550+0.260.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,059 associations by consensus.

CDC34 vs CCL14 — CCRCC

Per-sample scatter of CDC34 vs CCL14 in CCRCC (Pearson r = -0.29).

Explore this scatter interactively →

Exploration