CDC34

Across TCGA patient cohorts, CDC34 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC34-associated genes across cancer lineages are RNU6-1332P, RNU7-53P, and OR11H1. Each is linked with CDC34 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC34-to-partner and partner-to-CDC34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1332P grouped by CDC34-low versus CDC34-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC34→partner) and Y-score (partner→CDC34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1332P →	+0.208	+7.640	<.001	.009	3	1
BLCA	RNU7-53P →	+0.778	+7.640	<.001	.009	3	1
LUAD	OR11H1 →	+0.024	+7.930	<.001	.008	3	1
LUAD	LRRC34P2 →	+0.044	+7.930	<.001	.008	3	1
LUAD	RNU6-916P →	+0.288	+7.930	<.001	.008	3	1
LUAD	RNA5SP408 →	+0.308	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RNU6-1332P by CDC34 expression — BLCA

Explore this box plot interactively →