CDC25C

Across TCGA patient cohorts, CDC25C mutation is significantly associated with the RNA expression of many other genes, with 1,791 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC25C-associated genes across cancer lineages are RNU6-33P, CASTOR2, and MIR7702. Each is linked with CDC25C in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC25C-to-partner and partner-to-CDC25C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-33P grouped by CDC25C-low versus CDC25C-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25C→partner) and Y-score (partner→CDC25C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-33P →	+0.492	+3.965	.007	.006	3	3
UCEC	CASTOR2 →	+0.670	+2.202	.002	.001	3	2
UCEC	MIR7702 →	+0.163	+3.738	<.001	.009	3	2
READ	RNU4-80P →	+0.599	+3.827	<.001	.006	3	2
READ	CSH2 →	+0.020	+4.341	<.001	.007	3	2
BRCA	ATP6V0E1P3 →	+0.671	+4.082	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,791 associations by consensus.

RNU6-33P by CDC25C expression — READ

Explore this box plot interactively →