CDC25C

Across TCGA cell cohorts, CDC25C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,911 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CDC25C-associated GO terms across cancer lineages are Positive regulation of G2/MI transition of meiotic cell cycle, Regulation of mitotic nuclear division, and Regulation of mitotic sister chromatid separation. Each is linked with CDC25C in more than 19 cancer types. Because this analysis shows association rather than direction, both CDC25C-to-partner and partner-to-CDC25C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of G2/MI transition of meiotic cell cycle grouped by CDC25C-low versus CDC25C-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25C→partner) and Y-score (partner→CDC25C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.218	+0.679	<.001	.002	3	20
URINARY_TRACT	Regulation of mitotic nuclear division →	+0.136	+1.285	<.001	<.001	3	19
KIDNEY	Regulation of mitotic sister chromatid separation →	+0.189	+1.332	<.001	<.001	3	19
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.134	+1.186	<.001	.001	3	19
KIDNEY	Regulation of chromosome separation →	+0.192	+1.353	<.001	<.001	3	19
KIDNEY	Regulation of mitotic metaphase/anaphase transition →	+0.138	+1.186	<.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,911 associations by consensus.

Positive regulation of G2/MI transition of meiotic cell cycle by CDC25C expression — LIVER

Explore this box plot interactively →