CDC25C

Across TCGA cell cohorts, CDC25C mutation is significantly associated with the RNA expression of many other genes, with 92 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDC25C-associated genes across cancer lineages are TNRC6B, MTFMT, and IL7. Each is linked with CDC25C in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC25C-to-partner and partner-to-CDC25C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNRC6B grouped by CDC25C-low versus CDC25C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25C→partner) and Y-score (partner→CDC25C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNRC6B →	+0.705	+3.064	.004	.009	3	1
LARGE_INTESTINE	MTFMT →	+0.556	+3.212	.004	.006	3	1
LARGE_INTESTINE	IL7 →	+0.904	+3.299	.002	.004	3	1
LARGE_INTESTINE	SDHB →	+0.508	+3.299	.004	.004	3	1
LARGE_INTESTINE	TAF4B →	+0.730	+3.212	.006	.006	3	1
LARGE_INTESTINE	PELP1 →	+0.602	+3.212	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

TNRC6B by CDC25C expression — LARGE_INTESTINE

Explore this box plot interactively →