CDC25A

Across TCGA patient cohorts, CDC25A RNA expression is significantly associated with the protein abundance of many other proteins, with 26,165 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDC25A-associated proteins across cancer lineages are RFC2, RRM2, and RRP36_S73. Each is linked with CDC25A in more than 9 cancer types. Because this analysis shows association rather than direction, both CDC25A-to-partner and partner-to-CDC25A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC25A versus RFC2 in LSCC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25A→partner) and Y-score (partner→CDC25A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.473	+0.824	<.001	<.001	3	10
LUAD	RRM2 →	+0.960	+1.009	<.001	<.001	3	10
LSCC	RRP36_S73 →	+1.024	+1.032	<.001	<.001	3	10
OV	ATAD2_S342 →	+1.506	+0.836	<.001	.002	3	10
LUAD	SMC2 →	+0.714	+1.050	<.001	<.001	3	10
BRCA	SMC4 →	+0.686	+1.051	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,165 associations by consensus.

CDC25A vs RFC2 — LSCC

Explore this scatter interactively →