Across TCGA patient cohorts, CDC14C mutation is significantly associated with the RNA expression of many other genes, with 4,113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC14C-associated genes across cancer lineages are RNU6-110P, MIR7-3, and AATF. Each is linked with CDC14C in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC14C-to-partner and partner-to-CDC14C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14C→partner) and Y-score (partner→CDC14C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-110P →	+0.412	+4.270	.002	.008	3	3
HNSC	MIR7-3 →	+0.495	+5.224	.003	.001	3	3
UCEC	AATF →	+0.326	+3.144	.008	<.001	3	3
LUSC	CTU1 →	+0.499	+2.632	.002	.005	3	3
UCEC	POC1A →	+0.563	+3.906	.001	<.001	3	3
HNSC	H3P17 →	+0.134	+4.578	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,113 associations by consensus.

Exploration

CDC14C survival (RNA) · tumor vs normal (RNA) · all CDC14C data types