CDC14B

Across TCGA patient cohorts, CDC14B mutation is significantly associated with the RNA expression of many other genes, with 2,785 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC14B-associated genes across cancer lineages are RNU6-681P, MYCLP1, and FABP5P12. Each is linked with CDC14B in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC14B-to-partner and partner-to-CDC14B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-681P grouped by CDC14B-low versus CDC14B-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14B→partner) and Y-score (partner→CDC14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU6-681P →	+0.546	+5.039	<.001	.009	3	2
LGG	MYCLP1 →	+0.047	+5.846	<.001	.003	3	2
LGG	FABP5P12 →	+0.173	+5.266	<.001	.006	3	2
STAD	RNU6-458P →	+0.175	+5.417	<.001	.001	3	2
LIHC	RNU6-452P →	+0.640	+6.008	<.001	.002	3	2
UCEC	SNORA59B →	+0.166	+1.363	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,785 associations by consensus.

RNU6-681P by CDC14B expression — LGG

Explore this box plot interactively →