CDC14A

Across TCGA patient cohorts, CDC14A protein abundance is significantly associated with the RNA expression of many other genes, with 2,123 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CDC14A-associated genes across cancer lineages are SRSF5, HECW2, and ANKRD36C. Each is linked with CDC14A in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC14A-to-partner and partner-to-CDC14A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC14A versus SRSF5 in CCRCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14A→partner) and Y-score (partner→CDC14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SRSF5 →	+0.512	+0.645	.005	.002	3	3
CCRCC	HECW2 →	+1.106	+0.670	.007	<.001	3	2
LSCC	ANKRD36C →	+0.625	+0.326	.005	.006	3	2
BRCA	IMPDH2 →	+0.785	+0.890	.007	.006	3	2
BRCA	BCAS2P2 →	+0.656	+0.740	.008	.006	2	3
BRCA	RPS4XP14 →	+1.280	+0.541	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,123 associations by consensus.

CDC14A vs SRSF5 — CCRCC

Explore this scatter interactively →