CDC14A

Across TCGA patient cohorts, CDC14A mutation is significantly associated with the RNA expression of many other genes, with 3,285 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDC14A-associated genes across cancer lineages are RNU6-520P, DDAH1, and NOB1. Each is linked with CDC14A in more than 2 cancer types. Because this analysis shows association rather than direction, both CDC14A-to-partner and partner-to-CDC14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-520P grouped by CDC14A-low versus CDC14A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14A→partner) and Y-score (partner→CDC14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-520P →	+0.437	+4.243	.002	.009	3	3
UCEC	DDAH1 →	+0.547	+2.436	.004	.001	3	3
UCEC	NOB1 →	+0.525	+1.868	<.001	<.001	3	3
UCEC	MIR6803 →	+0.066	+3.571	<.001	.009	3	2
BRCA	RNA5SP463 →	+0.380	+4.513	<.001	.005	3	2
BRCA	CST2P1 →	+0.351	+7.473	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,285 associations by consensus.

RNU6-520P by CDC14A expression — BRCA

Explore this box plot interactively →