CDC14A

Across TCGA cell cohorts, CDC14A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,853 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CDC14A-associated GO terms across cancer lineages are Regulation of centrosome duplication, Regulation of chromosome organization, and Nuclear pore complex assembly. Each is linked with CDC14A in more than 13 cancer types. Because this analysis shows association rather than direction, both CDC14A-to-partner and partner-to-CDC14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome duplication grouped by CDC14A-low versus CDC14A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14A→partner) and Y-score (partner→CDC14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of centrosome duplication →	+0.078	+0.900	.001	.002	3	14
SOFT_TISSUE	Regulation of chromosome organization →	+0.091	+0.898	<.001	<.001	3	13
SOFT_TISSUE	Nuclear pore complex assembly →	+0.112	+0.704	<.001	<.001	3	12
SOFT_TISSUE	Regulation of microtubule-based process →	+0.041	+0.675	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.074	+0.789	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.072	+0.892	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,853 associations by consensus.

Regulation of centrosome duplication by CDC14A expression — LIVER

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