CDC14A

Across TCGA cell cohorts, CDC14A mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDC14A-associated genes across cancer lineages are ASZ1, BANF2, and MYL2. Each is linked with CDC14A in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC14A-to-partner and partner-to-CDC14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASZ1 grouped by CDC14A-low versus CDC14A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC14A→partner) and Y-score (partner→CDC14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ASZ1 →	+0.083	+2.982	.004	.007	3	2
BLOOD_Lymphoma	BANF2 →	+0.071	+4.643	<.001	.005	3	1
BLOOD_Leukemia	MYL2 →	+0.351	+2.982	<.001	.007	3	1
BLOOD_Leukemia	HRG →	+0.285	+3.177	<.001	.004	3	1
BLOOD_Leukemia	OLFM3 →	+0.598	+3.474	<.001	.007	3	1
BLOOD_Leukemia	KAAG1 →	+0.069	+3.177	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

ASZ1 by CDC14A expression — BLOOD_Leukemia

Explore this box plot interactively →