CDADC1

Across TCGA patient cohorts, CDADC1 mutation is significantly associated with the RNA expression of many other genes, with 3,691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDADC1-associated genes across cancer lineages are RNU6-178P, RNU6-128P, and RNA5SP414. Each is linked with CDADC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDADC1-to-partner and partner-to-CDADC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-178P grouped by CDADC1-low versus CDADC1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDADC1→partner) and Y-score (partner→CDADC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-178P →	+0.364	+5.063	.001	.001	3	3
COAD	RNU6-128P →	+0.537	+4.418	<.001	.008	3	2
LUSC	RNA5SP414 →	+0.338	+5.517	<.001	.001	3	2
UCEC	RNA5SP411 →	+1.236	+2.393	<.001	<.001	3	2
READ	IGHD5-12 →	+1.742	+5.421	<.001	.005	3	2
BRCA	RNU6-922P →	+0.356	+4.646	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

RNU6-178P by CDADC1 expression — HNSC

Explore this box plot interactively →