CDADC1

Across TCGA pan-cancer cohorts, CDADC1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CDADC1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CDADC1 RNA is repressed in tumor relative to normal tissue. In most cancer types CDADC1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRP are the cancer types where CDADC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDADC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	IV	−2.186	<.001	11	view →
KICH	Female	II,III,IV	−1.511	<.001	11	view →
KIRP	Male	III,IV	−1.100	<.001	9	view →
LUAD	Female	III,IV	−0.826	<.001	9	view →
BLCA	All	IV	−0.812	<.001	9	view →
LUSC	Female	II,III,IV	−0.919	<.001	8	view →
HNSC	All	III,IV	+0.406	.002	7	view →
BRCA	All	III,IV	−0.686	<.001	6	view →
KIRC	Male	All	−0.414	<.001	6	view →
COAD	Male	II,III,IV	+0.355	.001	5	view →
UCEC	All	All	−0.511	<.001	4	view →
CHOL	All	II,III,IV	+1.150	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CDADC1–THCA

Open the THCA breakdown →