CD93

Across TCGA patient cohorts, CD93 mutation is significantly associated with the RNA expression of many other genes, with 4,773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD93-associated genes across cancer lineages are METTL17, TOP3B, and E2F1. Each is linked with CD93 in more than 3 cancer types. Because this analysis shows association rather than direction, both CD93-to-partner and partner-to-CD93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL17 grouped by CD93-low versus CD93-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD93→partner) and Y-score (partner→CD93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	METTL17 →	+0.501	+3.333	.004	.005	3	4
SKCM	TOP3B →	+0.128	+1.507	<.001	.006	3	4
UCEC	E2F1 →	+0.586	+1.874	.003	.002	3	4
UCEC	TIMM44 →	+0.341	+2.705	<.001	<.001	3	4
UCEC	ACBD5 →	+0.533	+2.099	<.001	<.001	3	4
UCEC	PDCD10 →	+0.428	+2.016	.006	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,773 associations by consensus.

METTL17 by CD93 expression — LUAD

Explore this box plot interactively →