CD93

Across TCGA pan-cancer cohorts, CD93 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CD93’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CD93 RNA is repressed in tumor relative to normal tissue. In most cancer types CD93 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KIRC, and KICH are the cancer types where CD93 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CD93 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−2.302	<.001	11	view →
KIRC	Female	All	+1.629	<.001	11	view →
KICH	Male	All	−1.405	<.001	9	view →
LUSC	Female	II,III,IV	−2.958	<.001	8	view →
HNSC	Female	III,IV	+1.858	<.001	7	view →
LIHC	Female	II,III,IV	+1.409	<.001	7	view →
KIRP	Male	All	−1.357	<.001	7	view →
BLCA	Male	All	−1.088	.004	6	view →
BRCA	All	All	−0.656	<.001	6	view →
STAD	Male	II,III,IV	+1.222	<.001	5	view →
UCEC	All	All	−2.004	<.001	4	view →
READ	Male	All	+1.876	.025	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CD93–LUAD

Open the LUAD breakdown →