CD93

Across TCGA patient cohorts, CD93 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD93-associated genes across cancer lineages are 4E-BP1, Cyclin-D1, and ACC1. Each is linked with CD93 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD93-to-partner and partner-to-CD93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by CD93-low versus CD93-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD93→partner) and Y-score (partner→CD93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.270	+2.936	.001	<.001	3	2
COAD	Cyclin-D1 →	+0.184	+2.186	.001	.032	3	2
UCEC	ACC1 →	+0.329	+2.820	.004	.001	3	2
UCEC	Rad50 →	-0.164	-1.523	.034	.008	3	2
UCEC	Tuberin →	+0.218	+1.087	.011	.048	3	2
UCEC	C-Raf →	+0.125	+1.415	.006	.043	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

4E-BP1 by CD93 expression — UCEC

Explore this box plot interactively →