CD9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CD9 mutation is significantly associated with the RNA expression of many other genes, with 559 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD9-associated genes across cancer lineages are RNA5SP468, RNA5SP422, and MIR6499. Each is linked with CD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD9-to-partner and partner-to-CD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP468 grouped by CD9-low versus CD9-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD9→partner) and Y-score (partner→CD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNA5SP468 →+0.404+4.250<.001.00332
UCECRNA5SP422 →+0.888+2.863<.001<.00132
BRCAMIR6499 →+0.333+4.739<.001.00531
COADRNU6-1311P →+0.605+6.478<.001<.00131
COADTRAJ8 →+0.875+4.354.008.00731
COADOR2W2P →+0.067+5.122<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 559 associations by consensus.

RNA5SP468 by CD9 expression — BRCA

Box plot of RNA5SP468 in CD9-low vs CD9-high samples in BRCA.

Explore this box plot interactively →

Exploration