CD8B

Across TCGA patient cohorts, CD8B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,688 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD8B-associated proteins across cancer lineages are ZAP70, APOL3, and MYO1G. Each is linked with CD8B in more than 8 cancer types. Because this analysis shows association rather than direction, both CD8B-to-partner and partner-to-CD8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD8B versus ZAP70 in UCEC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD8B→partner) and Y-score (partner→CD8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZAP70 →	+0.810	+1.194	<.001	<.001	3	9
BRCA	APOL3 →	+0.781	+1.064	<.001	<.001	3	8
GBM	MYO1G →	+0.788	+0.468	<.001	<.001	3	8
GBM	ARHGAP15 →	+0.575	+0.298	<.001	<.001	3	8
OV	ARHGAP25 →	+0.912	+1.086	<.001	<.001	3	8
OV	ARHGAP30 →	+0.501	+0.816	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,688 associations by consensus.

CD8B vs ZAP70 — UCEC

Explore this scatter interactively →