CD8B

Across TCGA patient cohorts, CD8B protein abundance is significantly associated with the RNA expression of many other genes, with 752 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CD8B-associated genes across cancer lineages are XBP1, MYL9, and MID1. Each is linked with CD8B in more than 1 cancer types. Because this analysis shows association rather than direction, both CD8B-to-partner and partner-to-CD8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD8B versus XBP1 in LSCC, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD8B→partner) and Y-score (partner→CD8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XBP1 →	+0.947	+1.231	.007	.006	3	1
LSCC	MYL9 →	-1.228	-1.231	.001	.006	3	1
LSCC	MID1 →	-0.853	-1.231	.008	.006	3	1
LSCC	EMD →	-0.577	-1.187	.006	.009	3	1
LSCC	FGD1 →	-1.162	-1.187	.006	.009	3	1
LSCC	SRPX2 →	-0.852	-1.231	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 752 associations by consensus.

CD8B vs XBP1 — LSCC

Explore this scatter interactively →