CD82

Across TCGA patient cohorts, CD82 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD82-associated genes across cancer lineages are EGFR_pY1068, FOXO3a_pS318_S321, and ACC1. Each is linked with CD82 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD82-to-partner and partner-to-CD82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by CD82-low versus CD82-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD82→partner) and Y-score (partner→CD82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.290	-2.584	.008	.010	3	1
UCEC	FOXO3a_pS318_S321 →	-0.139	-2.807	.011	.003	3	1
UCEC	ACC1 →	+0.340	+3.013	.032	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.243	-2.794	<.001	.003	3	1
UCEC	Ku80 →	+0.295	+2.820	.004	.001	3	1
UCEC	Myosin-IIa_pS1943 →	+0.207	+1.598	.021	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

EGFR_pY1068 by CD82 expression — UCEC

Explore this box plot interactively →