CD82

Across TCGA pan-cancer cohorts, CD82 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CD82’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CD82 RNA is repressed in tumor relative to normal tissue. In most cancer types CD82 is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, COAD, and LUAD are the cancer types where CD82 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CD82 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−1.341	<.001	11	view →
COAD	Male	II,III,IV	+0.923	<.001	10	view →
LUAD	Male	All	−0.795	<.001	9	view →
KIRP	All	All	−1.110	<.001	6	view →
STAD	All	All	+0.947	.001	6	view →
READ	Male	All	+0.673	.026	5	view →
LIHC	All	III,IV	−0.552	.020	4	view →
PAAD	All	All	+1.012	.020	2	view →
PRAD	All	All	−0.651	<.001	2	view →
HNSC	All	All	+0.439	.015	2	view →
BRCA	Female	II,III,IV	−0.350	.036	2	view →
THCA	Male	IV	+0.643	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CD82–KIRC

Open the KIRC breakdown →