CD82

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CD82 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CD82-associated genes across cancer lineages are DMRTC2 and KRTAP4-11. Each is linked with CD82 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD82-to-partner and partner-to-CD82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTC2 grouped by CD82-low versus CD82-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD82→partner) and Y-score (partner→CD82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSDMRTC2 →+0.050+5.321.001.00531
CNSKRTAP4-11 →+0.584+4.981<.001.00831
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DMRTC2 by CD82 expression — CNS

Box plot of DMRTC2 in CD82-low vs CD82-high samples in CNS.

Explore this box plot interactively →

Exploration