CD81-AS1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CD81-AS1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CD81-AS1 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CD81-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CD81-AS1 expression acts as an unfavorable survival marker.

OV, ESCA, and SKCM are the cancer types where CD81-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSMedianII,III,IV0.0230.844<.00136view →
ESCAOSMedianAll0.1410.680.0043view →
SKCMDFSMedianIV0.0400.432.0383view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CD81-AS1–OV (OS)

Kaplan–Meier survival curve for CD81-AS1 mutant vs wild-type samples in OV.

Open the OV breakdown →

Exploration