Across TCGA pan-cancer cohorts, CD81-AS1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CD81-AS1 data layer compared with 23 for mass-spec protein.
The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CD81-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CD81-AS1 expression acts as an unfavorable survival marker.
OV, ESCA, and SKCM are the cancer types where CD81-AS1 Mutation most reproducibly stratifies survival.