CD81-AS1

Across TCGA pan-cancer cohorts, CD81-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CD81-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CD81-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CD81-AS1 is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.

KIRC, BLCA, and UCEC are the cancer types where CD81-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CD81-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.574	<.001	11	view →
BLCA	All	IV	−0.431	.005	7	view →
UCEC	All	III,IV	−0.899	<.001	6	view →
KIRP	All	III,IV	+0.324	.006	6	view →
BRCA	All	III,IV	−0.309	<.001	6	view →
KICH	Female	All	−0.328	<.001	5	view →
CHOL	All	All	+0.292	.004	4	view →
LUAD	All	IV	−0.280	.015	4	view →
HNSC	Male	All	+0.163	.011	4	view →
STAD	All	IV	−0.180	.025	2	view →
PRAD	All	All	−0.149	.002	2	view →
LUSC	All	All	−0.121	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CD81-AS1–KIRC

Open the KIRC breakdown →