CD79B

Across TCGA cell cohorts, CD79B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD79B-associated genes across cancer lineages are ACTRT1, KCNA4, and OR6C70. Each is linked with CD79B in more than 1 cancer types. Because this analysis shows association rather than direction, both CD79B-to-partner and partner-to-CD79B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTRT1 grouped by CD79B-low versus CD79B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD79B→partner) and Y-score (partner→CD79B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ACTRT1 →	+0.021	+5.201	<.001	.006	3	1
BLOOD_Leukemia	KCNA4 →	+0.028	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR6C70 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.124	+5.539	<.001	.003	3	1
BLOOD_Leukemia	MTRNR2L5 →	+0.033	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	OR1P1 →	+0.207	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ACTRT1 by CD79B expression — BLOOD_Leukemia

Explore this box plot interactively →